These are the two most similar product offerings so it makes sense to make them the basis for our comparison. In this article, we’re going to be comparing 2 key products within these application suites: Microsoft 365 (which is different than Office 365) and G Suite Business Edition when it comes to using them in a all Mac or Windows/Mac hybrid office environment. While they primarily deal with email, Office 365 and G-Suite have become much, much more than just email.